Table 3. Characteristics of individuals with a discrepancy in coronary heart disease risk using FRS and UKPDS.
| Characteristic | High risk using UKPDS but not FRS (n=46, 9.4%) |
High risk using FRS but not UKPDS (n=42, 8.6%) |
P value |
|---|---|---|---|
| Women | 17 (37) | 27 (64) | 0.010 |
| Age, yr | 54.3±9.7 | 57.2±5.6 | 0.080 |
| Age ≥50 | 35 (76.1) | 41 (98) | <0.001 |
| Body mass index, kg/m2 | 26.6±3.3 | 27.9±5.4 | 0.195 |
| Smoking | 10 (22) | 8 (19) | 0.755 |
| Glycosylated hemoglobin, % | 11.4±2.5 | 7.6±1.5 | <0.001 |
| Total cholesterol, mg/dL | 215±49 | 230±57 | 0.187 |
| High density lipoprotein cholesterol, mg/dL | 41±10 | 41±8 | 0.940 |
| Low density lipoprotein cholesterol, mg/dL | 123±34 | 131±41 | 0.378 |
| Triglycerides, mg/dL | 218±152 | 221±115 | 0.937 |
| Systolic blood pressure, mm Hg | 127±14 | 142±13 | <0.001 |
| Diastolic blood pressure, mm Hg | 80.41±9.23 | 89±10 | <0.001 |
| Hypertension >130/80 mm Hg | 14 (30) | 33 (79) | <0.001 |
Values are presented as number (%) or mean±standard deviation.
FRS, Framingham Risk score; UKPDS, United Kingdom Prospective Diabetes Study.
aP value indicates the comparison between males and females, where continuous variables are expressed in mean±standard deviation and assessed using unpaired t-test and categorical variables were expressed in percentages and assessed using chi-square test.