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. 2015 Jun 29;126(8):e1–e10. doi: 10.1182/blood-2015-03-632273

Table 1.

Sequence and cleavage sites of granzyme and caspase biosensors

Sensor name Predicted cleavage site Protease(s) predicted to cleave site
GLS.IEAD SGRIEADSESL Granzyme B; caspase 10
GLS.IETD SGIETDSGSL Granzyme B; caspase 8
GLS.VGPD SKSVGPDFGSL Granzyme B
GLS.DEVD SDEVDGSL Caspase 3/7
GLS.SGR GSSGRSGSL Granzyme A; granzyme K
GLS.PGPR GSPGPREGSL Granzyme A; granzyme K
GLS.QGPR GSQGPRGSL Granzyme A; granzyme K