Table 1.
The clinical characteristics of study subjects on unstandardized salt intake at baseline, after 4 weeks of a high salt diet, and after 4 weeks of a low salt diet in all subjects (Table 1a), in males (Table 1b), and females (Table 1c).
| Table 1a | ||||
|---|---|---|---|---|
| All subjects (n=39) | Baseline | High-salt (150 mmol per day) | Low-salt (50 mmol per day) | P* (high- vs. low-salt) |
| 24-hour SBP (mmHg) | 139 ± 13.3 | 136 ± 12.7 | 131 ± 11.1 | <0.0001 |
| 24-hour DBP (mmHg) | 86.3 ± 7.4 | 85.0 ± 7.0 | 82.3 ± 6.6 | 0.004 |
| Body weight (kg) | 79.5 ± 11.2 | 77.4 ± 10.7 | 77.3 ± 10.6 | 0.43 |
| Urine-Na+ (mmol/24h) | 165 ± 67.4 | 140 ± 39.5 | 50.7 ± 17.3 | <0.0001 |
| Urine-K+ (mmol/24h) | 75.0 ± 22.9 | 50.8 ± 11.3 | 50.9 ± 14.1 | 0.94 |
| Urine-Crea (mmol/24h) | 13.1 ± 3.3 | 12.3 ± 2.7 | 12.2 ± 3.0 | 0.65 |
| Serum-Na+ (mmol/L) | 140 ± 1.8 | 141 ± 1.5 | 139 ± 1.7 | <0.0001 |
| Serum-K+ (mmol/L) | 3.7 ± 0.26 | 3.6 ± 0.25 | 3.7 ± 0.30 | 0.21 |
| Serum-Crea (nmol/L) | 78.4 ± 12.8 | 80.4 ± 12.8 | 84.1 ± 12.6 | 0.001 |
| Table 1b. | ||||
|---|---|---|---|---|
| Male subjects (n=20) | Baseline | High-salt | Low-salt | P* (high- vs. low-salt) |
| 24-hour SBP (mmHg) | 138 ± 12.4 | 135 ± 13.1 | 130 ± 11.5 | 0.004 |
| 24-hour DBP (mmHg) | 87.2 ± 6.3 | 85.4 ± 7.1 | 82.4 ± 6.4 | 0.026 |
| Body weight (kg) | 85.3 ± 9.4 | 83.1 ± 8.7 | 82.8 ± 9.0 | 0.35 |
| Urine-Na+ (mmol/24h) | 175 ± 56.7 | 143 ± 44.8 | 49.5 ± 19.2 | <0.0001 |
| Urine-K+ (mmol/24h) | 76.8 ± 23.7 | 50.2 ± 9.0 | 50.8 ± 9.4 | 0.89 |
| Urine-Crea (mmol/24h) | 15.0 ± 3.3 | 14.1 ± 2.2 | 13.9 ± 3.2 | 0.73 |
| Serum-Na+ (mmol/L) | 141 ± 2.1 | 141 ± 1.5 | 139 ± 1.9 | <0.0001 |
| Serum-K+ (mmol/L) | 3.7 ± 0.29 | 3.7 ± 0.25 | 3.7 ± 0.28 | 0.85 |
| Serum-Crea (nmol/L) | 85.6 ± 10.4 | 87.4 ± 9.9 | 92.0 ± 9.3 | 0.001 |
| Table 1c. | ||||
|---|---|---|---|---|
| Female subjects (n=19) | Baseline | High-salt | Low-salt | P* (high- vs. low-salt) |
| 24-hour SBP (mmHg) | 140 ± 14.5 | 138 ± 12.6 | 132 ± 10.9 | 0.002 |
| 24-hour DBP (mmHg) | 85.4 ± 8.6 | 84.5 ± 7.0 | 82.3 ± 7.1 | 0.075 |
| Body weight (kg) | 73.4 ± 9.7 | 71.1 ± 9.2 | 71.5 ± 9.1 | 0.89 |
| Urine-Na+ (mmol/24h) | 154 ± 77.3 | 136 ± 33.9 | 51.9 ± 15.5 | <0.0001 |
| Urine-K+ (mmol/24h) | 72.9 ± 22.6 | 51.4 ± 13.7 | 50.9 ± 18.4 | 0.87 |
| Urine-Crea (mmol/24h) | 11.1 ± 1.8 | 10.4 ± 1.8 | 10.4 ± 1.4 | 0.78 |
| Serum-Na+ (mmol/L) | 140 ± 1.3 | 140 ± 1.5 | 140 ± 1.3 | 0.10 |
| Serum-K+ (mmol/L) | 3.7 ± 0.24 | 3.5 ± 0.23 | 3.7 ± 0.33 | 0.14 |
| Serum-Crea (nmol/L) | 70.9 ± 10.7 | 72.8 ± 11.4 | 75.7 ± 10.1 | 0.16 |
Values are means ± standard deviation (SD). P* - Refer to individual change of variable on high- as compared with on low-salt. SBP, systolic blood pressure; DBP, diastolic blood pressure; Crea, Creatinine.