Table 3.
Changes in plasma MBG (P-MBG) and urinary MBG (U-MBG) at baseline, high-salt, and low-salt intake in all subjects, and in males and females separately.
| Baseline | High-salt | Low-salt | P* (high- vs. low-salt) | |
|---|---|---|---|---|
| All subjects (n=39) | ||||
| P-MBG (pmol/L) | 111 (67.5–155) | 262 (175–367) | 233 (159–303) | 0.029 |
| UE-MBG (pmol/24 hours) | 1224 (796–1483) | 1080 (824–1321) | 1078 (709–1224) | 0.21 |
| Males (n=20) | ||||
| P-MBG (pmol/L) | 84.5 (63.0–158) | 279 (215–366) | 250 (124–305) | 0.067 |
| UE-MBG (pmol/24 hours) | 1301 (825–1722) | 1187 (935–1468) | 1133 (793–1362) | 0.15 |
| Females (n=19) | ||||
| P-MBG (pmol/L) | 124 (83.0–150) | 225 (146–367) | 214 (166–274) | 0.21 |
| UE-MBG (pmol/24 hours) | 1063 (780–1380) | 973 (678–1135) | 980 (634–1180) | 0.78 |
Values are medians (interquartile range). P* - Refer to individual change of variable on high- as compared with on low-salt. P-MBG, plasma concentration of marinobufagenin; UE-MBG, 24-hour urinary excretion of marinobufagenin