Table 3.
Neonatal outcome measures for infants (n = 19) of opioid-dependent mothers receiving methadone-assisted therapy.
| Participant no. | EGA,a weeks | Weight, g | Head circumference, cm | Length, cm | Apgar score (1 min) | Apgar score (5 min) | Time to NAS onset, h | Peak NAS score | Time to peak NAS score, h | NAS duration, h | NAS scores >4, % |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 38.3 | 2385 | 30.5 | 43.5 | 8 | 9 | 19.4 | 8 | 61.1 | 61.7 | 69.6 |
| 2 | 41.0 | 3140 | 34 | 51.0 | 8 | 9 | 16.0 | 8 | 16.0 | 25.0 | 66.7 |
| 3 | 38.9 | 4810 | 36 | 52.0 | 9 | 9 | 38.2 | 11 | 60.0 | 22.2 | 22.2 |
| 4 | 40.4 | 4370 | 36 | 51.0 | 8 | 9 | 12.7 | 6 | 30.7 | 45.0 | 28.6 |
| 5 | 30.4 | 1505 | 26 | 41.0 | 9 | 9 | 13.0 | 10 | 13.0 | 96.0 | 31.6 |
| 6 | 38.0 | 2515 | 30 | 48.0 | 9 | 9 | 23.2 | 6 | 23.2 | 48.0 | 13.6 |
| 7 | 33.3 | 2125 | 30 | 43.5 | 8 | 9 | 40.4 | 8 | 40.4 | 12.0 | 25.0 |
| 8 | 40.0 | 4025 | 35.5 | 49.0 | 9 | 9 | 26.0 | 9 | 69.7 | 59.5 | 47.8 |
| 9 | 39.3 | 2865 | 32 | 46.0 | 8 | 8 | 19.0 | 7 | 30.0 | 556.0 | 84.5 |
| 10 | 35.0 | 2740 | 32 | 50.0 | 8 | 8 | 54.0 | 6 | 54.0 | 22.0 | 18.5 |
| 11 | 40.0 | 2675 | 34 | 48.0 | 8 | 9 | 127.8 | 7 | 166.3 | 49.0 | 6.3 |
| 12 | 37.0 | 3110 | 34 | 50.0 | 7 | 9 | 30.0 | 15 | 75.8 | 58.5 | 12.7 |
| 13 | 32.0 | 2080 | 32 | 45.0 | 9 | 9 | 6.3 | 10 | 119.6 | 113.3 | 66.7 |
| 14 | 39.0 | 3760 | 34.5 | 51.0 | 9 | 9 | 23.5 | 11 | 30.5 | 86.7 | 55.8 |
| 15 | 36.0 | 3650 | 33 | 52.5 | 9 | 9 | 28.5 | 19 | 194.0 | 289.5 | 66.7 |
| 16 | 34.0 | 2745 | 33 | 48.0 | 8 | 8 | —b | 4 | 16.5 | — | — |
| 17 | 31.0 | 2850 | 33 | 47.0 | 8 | 9 | 60.7 | 8 | 80.7 | 154.5 | 51.4 |
| 18 | 35.0 | 3180 | 34 | 52.0 | 7 | 9 | 13.3 | 14 | 77.3 | 320.5 | 90.1 |
| 19 | 32.0 | 2995 | 33 | 49.0 | 8 | 9 | 3.5 | 14 | 89.5 | 341.0 | 89.7 |
| Mean | 36.3 | 3027.6 | 32.8 | 48.3 | 8.3 | 8.8 | 30.9 | 9.5 | 65.7 | 131.1 | 47.1 |
| SD | 3.4 | 816.3 | 2.4 | 3.3 | 0.7 | 0.4 | 28.6 | 3.8 | 49.8 | 148.5 | 28.0 |
| Median | 37.0 | 2865.0 | 33.0 | 49.0 | 8.0 | 9.0 | 23.4 | 8.0 | 60.0 | 60.6 | 49.6 |
EGA, estimated gestational age at birth.
Dashes indicate data not available.