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. Author manuscript; available in PMC: 2015 Aug 21.
Published in final edited form as: J Trauma Acute Care Surg. 2014 Apr;76(4):982–990. doi: 10.1097/TA.0000000000000163

Figure 4.

Figure 4

Clodronate pretreatment worsens permeability injury in mice with LC. Mice receiving clodronate pretreatment (100 μL of 0.2 mg/mL) IP injection 48 hours before LC showed increase alveolar/endothelial permeability to albumin recovered in BAL. These effects were mostly noted at 5-hour and 24-hour peak closely following other inflammatory attributes (P/V curves, BAL cellularity). One-way ANOVA versus uninjured control (n = 9, *p < 0.05. **p < 0.01. ***p < 0.001). One-way ANOVA versus liposome (n = 9, ##p < 0.01).