Table 4. Association between type-specific HPV seropositivity and SCC.
| HPV genus/type | Controls (N = 300) n (%) |
SCC (N = 173) | Pb | |
|---|---|---|---|---|
|
| ||||
| n (%) | OR (95% CI)a | |||
| Any HPV type | 256 (85.3) | 161 (93.1) | 2.50 (1.21–5.15) | 0.01 |
| Alpha | ||||
| 2 | 29 (9.7) | 15 (8.7) | 0.77 (0.37–1.61) | 0.49 |
| 3 | 36 (12.0) | 24 (13.9) | 1.21 (0.65–2.24) | 0.55 |
| 7 | 22 (7.3) | 15 (8.7) | 1.09 (0.50–2.35) | 0.83 |
| 10 | 17 (5.7) | 19 (11.0) | 2.24 (1.04–4.85) | 0.04 |
| 27 | 33 (11.0) | 29 (16.8) | 1.78 (0.97–3.26) | 0.06 |
| 57 | 22 (7.3) | 16 (9.2) | 1.42 (0.66–3.07) | 0.37 |
| 77 | 47 (15.7) | 33 (19.1) | 1.36 (0.79–2.35) | 0.27 |
| Beta (β) | ||||
| Any β1 | 100 (33.3) | 85 (49.1) | 1.86 (1.22–2.85) | 0.004 |
| 5 | 38 (12.7) | 35 (20.2) | 1.68 (0.95–2.96) | 0.07 |
| 8 | 69 (23.0) | 63 (36.4) | 1.80 (1.14–2.84) | 0.01 |
| 20 | 63 (21.0) | 51 (29.5) | 1.41 (0.88–2.27) | 0.16 |
| 24 | 37 (12.3) | 36 (20.8) | 1.63 (0.93–2.86) | 0.09 |
| 36 | 52 (17.3) | 40 (23.1) | 1.13 (0.68–1.90) | 0.64 |
| Any β2 | 143 (47.7) | 91 (52.6) | 1.30 (0.86–1.97) | 0.21 |
| 9 | 75 (25.0) | 51 (29.5) | 1.17 (0.74–1.85) | 0.51 |
| 15 | 76 (25.3) | 50 (28.9) | 0.93 (0.58–1.49) | 0.77 |
| 17 | 77 (25.7) | 61 (35.3) | 1.59 (1.02–2.49) | 0.04 |
| 23 | 61 (20.3) | 42 (24.3) | 1.23 (0.75–2.02) | 0.42 |
| 38 | 74 (24.7) | 42 (24.3) | 0.94 (0.58–1.52) | 0.79 |
| 107 | 48 (16.0) | 31 (17.9) | 0.91 (0.52–1.58) | 0.73 |
| Any β3 | 101 (33.7) | 73 (42.2) | 1.38 (0.90–2.11) | 0.14 |
| 49 | 89 (29.7) | 65 (37.6) | 1.36 (0.88–2.11) | 0.16 |
| 75 | 46 (15.3) | 31 (17.9) | 1.04 (0.60–1.81) | 0.89 |
| 76 | 54 (18.0) | 41 (23.7) | 1.24 (0.74–2.05) | 0.41 |
| β4 (92) | 50 (16.7) | 37 (21.4) | 1.29 (0.76–2.18) | 0.35 |
| β5 (96) | 45 (15.0) | 44 (25.4) | 1.64 (0.97–2.76) | 0.06 |
| Gamma | ||||
| 4 | 103 (34.3) | 75 (43.4) | 1.49 (0.97–2.28) | 0.07 |
| 48 | 64 (21.3) | 48 (27.7) | 1.56 (0.96–2.53) | 0.07 |
| 50 | 47 (15.7) | 27 (15.6) | 0.90 (0.51–1.59) | 0.72 |
| 65 | 78 (26.0) | 55 (31.8) | 1.20 (0.76–1.90) | 0.42 |
| 88 | 20 (6.7) | 14 (8.1) | 1.23 (0.55–2.73) | 0.61 |
| 95 | 67 (22.3) | 40 (23.1) | 0.97 (0.60–1.59) | 0.92 |
| 101 | 33 (11.0) | 24 (13.9) | 1.20 (0.64–2.26) | 0.57 |
| 103 | 13 (4.3) | 9 (5.2) | 0.92 (0.35–2.41) | 0.86 |
| Mu (1) | 96 (32.0) | 66 (38.2) | 1.41 (0.91–2.18) | 0.13 |
| Nu (41) | 34 (11.3) | 21 (12.1) | 0.91 (0.48–1.74) | 0.78 |
NOTE: The ORs and 95% CIs for the associations between type-specific HPV seropositivity and SCC.
a
OR and 95% CI adjusted for age and sex.
b
P value for β-coefficient corresponding to HPV term in logistic regression model.