Table 1. Table of TJ proteins whose overexpression has been reported to promote tumorigenesis in specific cancers.
| Proteins | Cancer | Reference |
|---|---|---|
| JAM-A | Brain | (24) |
| Breast | (25-30) | |
| Cancer stem cells | (31) | |
| Gastric | (32) | |
| Lung | (33) | |
| Nasopharyngeal | (34) | |
| JAM-C | Fibrosarcoma | (35) |
| Lung | (36) | |
| Melanoma | (37-39) | |
| Ovarian | (40) | |
| CAR | Breast | (41,42) |
| Endometrial | (43) | |
| Lung | (44) | |
| Oral | (45) | |
| Ovarian | (46) | |
| Thyroid | (47) | |
| Claudin-1 | Breast | (48-50) |
| Cervical | (51) | |
| Colorectal | (52-59) | |
| Gastric | (60) | |
| Liver | (61) | |
| Oral | (15) | |
| Ovarian | (62) | |
| Claudin-2 | Breast | (63-66) |
| Colorectal | (52,67) | |
| Lung | (68,69) | |
| Skin | (70) | |
| Claudin-3 | Breast | (71,72) |
| Colorectal | (73) | |
| Endometrial | (74,75) | |
| Gastric | (76) | |
| Kidney | (71) | |
| Lung | (71) | |
| Ovarian | (16,71,77-81) | |
| Prostate | (71) | |
| Uterine | (75) | |
| Claudin-4 | Breast | (71) |
| Endometrial | (74,82) | |
| Gastric | (71,76,83) | |
| Lung | (71) | |
| Kidney | (71) | |
| Nasopharyngeal | (84) | |
| Ovarian | (16,71,77,79) | |
| Pancreatic | (71,85) | |
| Uterine | (75) | |
| Claudin-7 | Cervical | (51) |
| Colon | (86) | |
| Gastric | (71) | |
| Liver | (71) | |
| Lung | (71) | |
| Nasopharyngeal | (84) | |
| Ovarian | (71,87) | |
| Pancreatic | (71,88) | |
| Thyroid | (71) | |
| Claudin-11 | Gastric | (89) |
| Claudin-16 | Breast | (90) |
| Ovarian | (91) | |
| Renal | (92) | |
| Claudin-20 | Breast | (93) |