Table 1.
Effect of MEMA leaves on castor oil-induced diarrhea in rats.
| Group | Treatment | Total number of feces |
% Inhibition of defecation |
Total number of diarrheal feces |
% Inhibition of diarrhea |
|---|---|---|---|---|---|
| I | Castor oil + Saline (2 mL/kg p.o) |
18.18 ± 1.91∗∗ | — | 11.05 ± 1.08∗∗ | — |
|
| |||||
| II | Castor oil + Loperamide (5 mg/kg i.p) |
7.76 ± 0.66∗∗ | 57.32 | 5.00 ± 0.33∗∗ | 54.75 |
|
| |||||
| III | Castor oil + Leaves Extract (200 mg/kg i.p) |
10 ± 0.81∗∗ | 44.99 | 6.33 ± 0.93∗∗ | 42.67 |
|
| |||||
| IV | Castor oil + Leaves Extract (400 mg/kg i.p) |
8 ± 1.52∗∗ | 55.99 | 5.79 ± 0.52∗∗ | 57.75 |
Values were expressed as mean ± SEM. (n = 5). ∗ p < 0.05, ∗∗ p < 0.01 when compared with control group (ANOVA followed by Dunnett's t-test).