Figure 4. TH improves brain volumes at 2 weeks except for hippocampus.

Volumes of healthy brain tissue in contralateral (white bars) and ipsilateral (black bars) hemispheres were calculated from 2 week MRI images as described in Methods. A: Moderate, B: Severe; depicting volumes for: a, whole hemisphere; b, cortex; c, thalamus-striatum; d, hippocampus. TH reduced brain volume loss for all regions except hippocampus, *p<0.05, ANOVA. C: Paired ipsilateral/contralateral ratios, for normothermic (white bars) and TH (black bars) for: a, Moderate; b, Severe cohorts; * p< 0.05.