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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Mol Cancer Res. 2015 May 20;13(8):1206–1217. doi: 10.1158/1541-7786.MCR-15-0169

Figure 1.

Figure 1

19p13.3 deletion associated ZBTB7A down-regulation contributes to melanoma metastasis and poor prognosis. A, list of significant chromosomal focal deletions in human melanoma based on The Cancer Genome Atlas (TCGA) skin cutaneous melanoma SNP array dataset. GISTIC q-values (x-axis) are plotted across different chromosome (y-axis). B, 19p13.3 CNV status in primary and metastatic melanoma based on TCGA SNP array database, error bars represent mean ± s.e.m. C, kaplan–Meier overall survival curve of patients with and without 19p13.3 deletion based on TCGA melanoma dataset. D, expression of 19p13.3 cancer genes STK11, TCF3, FSTL3, GNA11, SIRT6 and ZBTB7A during the progression of human melanoma, error bars represent mean ± s.e.m.