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. 2015 Jul 6;172(16):4173–4188. doi: 10.1111/bph.13203

Figure 8.

Figure 8

TSP1−/− mice are protected from adMyrAkt1-induced pulmonary fibrosis. (A) Masson's trichrome staining of WT and TSP1−/− mouse lung harvested 14 days after i.t. adenovirus gene transfer of control vector or adMyrAkt1 (constitutive active Akt1) (n = 3 mice/group). (B and C) Per cent fibrosed area quantified using ImageJ software, and Ashcroft fibrosis score of the degree of fibrosis in WT and TSP1−/− mice subjected to control vector or adMyr-Akt1 respectively. *P < 0.05, #P < 0.01, ▲P < 0.001.