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. 2015 Jul 8;172(16):4189–4199. doi: 10.1111/bph.13204

Figure 5.

Figure 5

(A) Concentration-dependent inhibition of PO4-induced VICs mineralization by QPS1 (n = 7). (B) Alizarin red staining of VIC cultures. (C) Percentage of ATP in VIC supernatants (n = 4). (D) QPS1 prevented PO4-induced apoptosis of VICs as evaluated with the caspase3/7 assay (n = 4). (E and F) QPS1 (10 μM) significantly reduced the rise of osteogenic/fibrotic markers following a treatment of VICs with PO4 (n = 3). Data are mean ± SEM. In A and D, *P < 0.05 compared with control (CTL), #P < 0.05 compared with CTL with QPS, ‡P < 0.05 compared with PO4; in panels E and F, *P < 0.05 compared with control (CTL), #P < 0.05 compared with PO4 without QPS.