Dexamethasone treatment results in decreased lean mass and increased fat mass in mice. Weekly body weight (A), lean mass (B), fat mass (C) and percent fat (D) from control (black) and dexamethasone (red) treated mice. (E) Average food consumption per mouse per day. (F) Insulin tolerance test. Following a 6-h fast, insulin (1 mU/g) was administered via i.p. injection, and blood glucose was measured at baseline and the indicated time post injection. (G) Inguinal (IWAT) and epididymal (EWAT) fat pad weights, for right fat pads only. *P<0.05.