Table 3.

Summarized gene set enrichment analysis of pathways. Selected pathway enriched in subcutaneous adipose tissue from Cushing's disease patients via GSEA analysis. For a complete list, see Supplementary Tables 2 and 3

Pathway	Dataset	NES
M_PHASE_OF_MITOTIC_CELL_CYCLE	Gene ontology	2.60*
KEGG_CITRATE_CYCLE_TCA_CYCLE	KEGG	2.41*
KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS	KEGG	2.41*
REACTOME_TRIGLYCERIDE_BIOSYNTHESIS	Reactome	2.24*
PYRUVATE_METABOLISM	Gene ontology	2.24*
KEGG_VALINE_LEUCONE_AND_ISOLEUCINE_DEGRADATION	KEGG	2.16*
STEROID_BIOSYNTHETIC_PROCESS	Gene ontology	2.11*
KEGG_STARCH_AND_SUCROSE_METABOLISM	KEGG	2.08*
PROTEASOME_COMPLEX	Gene ontology	1.78*
KEGG_ALLOGRAFT_REJECTION	KEGG	−1.87*
KEGG_BASAL_CELL_CARCINOMA	KEGG	−1.86*
KEGG_RIBOSOME	KEGG	−2.33*

NES, net enrichment score; *q<0.25.