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. 2015 Aug 8;6(10):962–969. doi: 10.7150/jca.12266

Figure 1.

Figure 1

Expression of human IL-37 suppressed the proliferation and invasion of HPV+ Hela and HPV- C33A cells. (A, B) Transfection of IL-37 increased the mRNA expression of IL-37 in Hela (A) and C33A (B) cells. (C, D) Transfection of IL-37 increased the protein expression of IL-37 in Hela (C) and C33A (D) cells. (E, F) IL-37 inhibited the cell proliferation of Hela (E) and C33A (F) cells. (G, H) IL-37 suppressed the cell invasion of Hela (G) and C33A (H) cells. (I) IL-37 showed higher anticancer ability to suppress cell proliferation in HPV+ Hela cells than that in HPV- C33A cells. (J) IL-37 showed higher anticancer ability to suppress cell invasion in HPV+ Hela cells than that in HPV- C33A cells. (N=3). NC: normal control gourp (transfection of blank expression vector). IL-37: IL-37 gene transfection group.