Dose–response effects of PT-141 on the sexual behavior of E+P-primed female rats in unilevel pacing chambers. (Top Left) Effects on solicitations (F3,34 = 6.62, P < 0.002). (Top Right) Effects on hops and darts (F3,34 = 4.12, P < 0.02). Post hoc tests revealed that both the 100- and 200-μg/kg doses increased solicitation and hops and darts significantly (P values < 0.05). (Middle Left) Effects on lordosis quotients. (Middle Right) Effects on female mounting of the male (FMM). F3,34 = 3.84, P < 0.02. Post hoc tests revealed a significant effect of the highest dose only (P < 0.05). (Bottom Left) Effects on the intromission return latency. (Bottom Right) Effects on the ejaculation return latency). F3,34 = 3.65, P < 0.02. Post hoc tests revealed a significant effect of the 100- and 200-μg/kg doses (P values < 0.05) Data are means ± SEM. *, P < 0.05 from control.