Table 1.

Patient characteristics

	Suspected	Confirmed	Transformed at time of diagnosis	No transformation
	n = 232	n = 147	n = 47	n= 2273
Extranodal sites
≤1	171 (74%)	100 (68%)	39 (83%)	1801 (79%)
>1	52 (22%)	43 (29%)	4 (9%)	394 (17%)
Not done/missing	9 (4%)	4 (3%)	4 (9%)	78 (3%)
Nodal sites
≤4	131 (56%)	86 (59%)	31 (66%)	1463 (64%)
>4	88 (38%)	58 (39%)	15 (32%)	718 (32%)
Not done/missing	13 (6%)	3 (2%)	1 (2%)	92 (4%)
Grade
I/II	170 (73%)	103 (70%)	9 (19%)	1632 (72%)
III	37 (16%)	23 (16%)	7 (15%)	428 (19%)
Unknown/missing	25 (11%)	21 (14%)	31 (66%)	213 (9%)
ECOG PS
0-1	126 (54%)	89 (61%)	33 (70%)	1525 (67%)
≥2	11 (5%)	6 (4%)	2 (4%)	70 (3%)
Not done/missing	95 (41%)	52 (35%)	12 (26%)	678 (30%)
Hb
<12 g/dL	49 (21%)	37 (25%)	10 (21%)	434 (19%)
≥12 g/dL	162 (70%)	101 (69%)	37 (79%)	1692 (74%)
Not done/missing	21 (9%)	9 (6%)	0	147 (6%)
LDH
Normal	130 (56%)	72 (49%)	25 (53%)	1393 (61%)
>ULN	37 (16%)	31 (21%)	12 (26%)	358 (16%)
Not done/missing	65 (28%)	44 (30%)	10 (21%)	522 (23%)
Stage
I/II	66 (28%)	35 (24%)	14 (30%)	761 (33%)
III/IV	163 (70%)	111 (76%)	33 (70%)	1489 (66%)
Not done/missing	3 (1%)	1 (1%)	0	23 (1%)
B symptoms
No	162 (70%)	103 (70%)	33 (70%)	1716 (75%)
Yes	70 (30%)	44 (30%)	14 (30%)	557 (25%)
Age
<60	91 (39%)	62 (42%)	18 (38%)	1028 (45%)
60-69	55 (24%)	46 (31%)	14 (30%)	582 (26%)
70-79	55 (24%)	33 (22%)	6 (13%)	448 (20%)
80+	31 (13%)	6 (4%)	9 (19%)	215 (9%)
FLIPI
0-1	48 (21%)	23 (16%)	12 (26%)	679 (30%)
2	55 (24%)	38 (26%)	10 (21%)	549 (24%)
3-5	73 (31%)	52 (35%)	17 (36%)	602 (26%)
Missing	56 (24%)	34 (23%)	8 (17%)	443 (19%)

Hb, hemoglobin; LDH, lactate dehydrogenase; PS, performance status; ULN, upper limit of normal.