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. 2015 Aug 21;5:13041. doi: 10.1038/srep13041

Figure 2. B cells and serum anti-GPI antibodies in Padi4 KO mice after the GPI immunization.

Figure 2

(A) The number of B220+ B cells in spleens was counted 0, 7, and 14 days after the immunization. Pre-immunized (WT n = 3, Padi4 KO n = 3), 7 days after the immunization (WT n = 6, Padi4 KO n = 6), 14 days after the immunization (WT n = 11, Padi4 KO n = 13). (B–D) The titers of serum anti-GPI IgM, IgG antibodies and anti-CCP2 IgG antibodies were measured before and 14 days after the immunization. Pre-immunized (WT n = 3, Padi4 KO n = 3), 14 days after the immunization (WT n = 13, Padi4 KO n = 13), N.D.: not detected. *p < 0.05.