Table 3.

List of compounds active and inactive on Toll-like receptor 7 and whether or not the compounds contain the pharmacophore hypothesis

Compound	Structure	Activity on TLR7	Pharmacophore
5		Yes	No
6a		No	No
6b		No	No
11a		No	No
11b		No	No
17		No	No
19a		Yes	Yes
19b		Yes	Yes
19c		Yes	Yes
19d		Yes	Yes
19e		Yes	Yes
19f		Yes	Yes
19g		Yes	Yes
19h		Yes	Yes
19i		Yes	Yes
19j		Yes	Yes
19k		Yes	Yes
19l		Yes	Yes
19m		Yes	Yes
19n		No	Yes
19o		Yes	Yes
19p		Yes	Yes
19q		Yes	Yes
19r		Yes	Yes
19s		No	Yes
23a		Yes	No
23b		No	No
23c		No	Yes
23d		No	No
23e		No	No
23f		No	No
23g		Yes	No
23h		Yes	No
23i		No	Yes
23j		Yes	No
30		Yes	No

True positive = 17; false positive = 4; true negative = 9; false negative = 6.