Thrombocytopaenia |
>50% fall or nadir ≥20 ×109/l |
30–50% fall or nadir 10–19×109/l |
<30% fall or nadir < 10 ×109/l |
Timing of the decrease in platelet count |
Day 5 to 10 or ≤day 1 with recent heparin (past 30 days) |
>Day 10 or timing unclear or < day 1 if heparin exposure within 30–100 days |
<Day 4 with no recent heparin use |
Thrombosis or other sequelae |
Proven thrombosis, skin necrosis, or acute systemic reaction after heparin bolus |
Progressive, recurrent, or silent thrombosis; erythematous skin lesions |
None |
Other causes of thrombocytopenia |
None evident |
Possible |
Definitive |