Table 2.
Parameters used in Equations (1) and (2).
Parameter | Description | Value | Nondimensionalized |
---|---|---|---|
k1 | Collagen assembly | 0.1 day−1 | 0.1 |
k2 | Number of nucleators per collagen molecule | 1 | 1 |
k3 | Formation of hydroxyapatite molecules | 1000 day−1 | 1 |
υ1 | Production of inhibitors by osteoblasts | 0.1 day−1 | 0.1 |
r1 | Degradation of inhibitors | 2 × 10−7 day−1 | 0.2 |
R2 | Use of nucleators by mineralized bone | 1.7 × 10−8mol−1 | 12 |
a | Hill coefficient | 10 | 10 |
b | Apparent dissociation constant for Hill function | 1057 | 0.001 |