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. 2015 Jan 23;56(1):587–597. doi: 10.1167/iovs.14-15594

Table 3.

Effects of Chloroquine and Cyanide on Retinal Layer Thickness

Layer
Drug
Control,n= 6
10 μM Chloroquine,n= 5
3 mM NaCN,n= 5
IPL +3 ± 10% +7 ± 10% +4 ± 9%
INL −7 ± 43% −7 ± 35% +9 ± 18%
OPL +5 ± 19% +17 ± 17%* −8 ± 15%
ONL +9 ± 15% −2 ± 17% +6 ± 8%
IS −2 ± 6% −9 ± 9% 0 ± 10%
OS +1 ± 11% 0 ± 12% +9 ± 6%*
PRT to RPE −36 ± 14%* +7 ± 11% −27 ± 19%*

Comparisons of relative change in average retinal layer thickness before and after the drug application.

*

Significant changes in layer thickness (1-tailed paired t-test, P ≤ 0.05).