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. 2015 Aug 14;9:4709–4717. doi: 10.2147/DDDT.S86616

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© 2015 Lin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Changes of behavioral and pain tests in rats with SCI by metformin.

Notes: The rats receiving SCI was further treated with metformin (320 mg/kg) intravenously once daily for 28 days. Responses show (A) BBB locomotor scale, (B) inclined plane test, (C) limb hanging test, and (D) pain test. Values (mean ± SE) were obtained from each group of six rats. Each group compared with the vehicle-treated SCI rats without statistical difference.

Abbreviations: BBB, Basso, Beattie and Bresnahan; SCI, spinal cord injury; SE, standard error.