Shape of association of inflammation markers with common carotid artery intima-media thickness (CCA-IMT). Panel (a): baseline inflammatory markers and baseline CCA-IMT; panel (b): baseline inflammatory markers and yearly CCA-IMT progression; panel (c): change in inflammatory markers and yearly CCA-IMT progression.
aModels in panel (c) were additionally adjusted for mean CCA-IMT.
bModels in panels (a) and (b) were further adjusted for baseline traditional risk factors (i.e. systolic blood pressure, total cholesterol, history of diabetes, current smoking, use of anti-hypertensive medication), models in panel (c) for means and changes in traditional risk factors.
hsCRP: high-sensitivity C-reactive protein; CI: confidence interval