Associations between number of elevated inflammation markers at baseline and common carotid artery intima-media thickness (CCA-IMT). Panel (a): baseline inflammatory load and baseline CCA-IMT; panel (b): baseline inflammatory load and yearly CCA-IMT progression. For each of the three inflammatory markers (high-sensitivity C-reactive protein, fibrinogen, leucocyte count), levels were deemed to be elevated if they were in the top two fifths of the study-specific distribution. People with no elevated inflammatory markers served as the reference group. Models were adjusted for baseline age, sex, systolic blood pressure, total cholesterol, history of diabetes, current smoking, and use of anti-hypertensive medication.
CI: confidence interval