Table 5.
Performance challenge classifications (n=35) at ±25% and ±50% of each evaluated cutoff (5 & 10 µg/L) in each evaluated matrix (Urine & Phosphate Buffered Saline) across 35 plates.
| Cutoffs (µg/L) |
JWH-018 N-(5-hydroxypentyl) metabolite Performance Challenge concentration (µg/L) in urine |
Correct classification (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2.5 | 3.75 | 5.0 | 6.25 | 7.5 | 12.5 | 15 | Negative | Positive | |||
| −50% | −25% | +25% | +50% | ||||||||
| 5-PBS | 25/35 (−) | 5/35 (−) | - | 34/35 (+) | 32/35 (+) | - | - | 71 | 14 | 97 | 91 |
| 5-UR | 35/35 (−) | 30/35 (−) | - | 24/35 (+) | 23/35 (+) | - | - | 100 | 86 | 69 | 66 |
| 10-PBS | - | - | 29/35 (−) | - | 27/35 (−) | 33/35 (+) | 35/35 (+) | 83 | 77 | 94 | 100 |
| 10-UR | - | - | 35/35 (−) | - | 35/35 (−) | 34/35 (+) | 34/35 (+) | 100 | 100 | 97 | 97 |
(−) = Negative result
(+) = Positive result
PBS = Phosphate Buffered Saline
UR= Urine