(a) Patients with normal IGF1 levels on EDIs at weeks 24 (end of phase 1) and 48 (end of study). (b) Serum IGF1 levels (% of ULN) according to allocated injection schedule for lanreotide Autogel 120 mg in phase 2. Data are from the ITT population. DI, dosing interval; EDI, extended dosing interval; IGF1, insulin-like growth factor-1; ITT, intention to treat; LVA, last post-baseline value available; ULN, upper limit of normal.