Table 1.
Characteristics and laboratory data for study participants
| Metformin group n=25 | Control group n=25 | P-value | |
|---|---|---|---|
| Sex (male/female) | 17/8 | 11/14 | 0.087 |
| Age (years) | 52.52±9.16 | 52.84±9.34 | 0.903 |
| BMI (kg/m2) | 24.93±3.50 | 25.06±2.60 | 0.887 |
| Waist (cm) | 91.75±10.81 | 86.98±5.44 | 0.081 |
| WHR | 0.93±0.07 | 0.90±0.04 | 0.125 |
| Systolic BP (mmHg) | 122.96±17.46 | 119.20±9.82 | 0.355 |
| Diastolic BP (mmHg) | 75.42±13.75 | 80.68±5.57 | 0.083 |
| HbA1c (%) | 7.43±0.61 | 5.73±0.24 | 0.000* |
| TC (mmol/L) | 4.55±0.78 | 4.14±0.61 | 0.048* |
| TG (mmol/L) | 1.78±0.79 | 0.99±0.40 | 0.000* |
| HDL-C (mmol/L) | 1.16±0.24 | 1.40±0.30 | 0.004* |
| LDL-C (mmol/L) | 2.79±0.58 | 2.35±0.50 | 0.007* |
| Apelin (ng/mL) | 6.09±4.90 | 1.93±1.81 | 0.000* |
Notes: Data presented as mean ± standard deviation or as a ratio.
*
P-value <0.05.
Abbreviations: BP, blood pressure; BMI, body mass index; WHR, waist to hip ratio; HbA1c, glycosylated hemoglobin; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol.