Table 2.

Clinical and biochemical parameters at baseline and at the end of the study

	Baseline	12 weeks	24 weeks	P1 n=25	P2 n=24	P3 n=24
HbA1c (%)	7.43±0.61	6.78±0.74	6.82±0.73	0.005*	0.008*	0.057
FPG (mmol/L)	7.35±0.85	6.53±0.76	6.58±1.13	0.037*	0.041*	0.12
FINS (µU/mL)	7.74±4.38	8.12±4.12	9.04±4.08	0.545	0.890	0.890
HOMA-% B	48.66±21.10	56.43±26.32	64.88±34.44	0.656	0.481	0.481
HOMA-IR	1.29±0.72	1.38±0.59	1.47±0.66	0.872	0.673	0.958
TC (mmol/L)	4.55±0.78	4.78±0.82	4.47±0.48	0.812	0.465	0.873
TG (mmol/L)	1.78±0.79	2.03±0.67	1.98±0.78	0.954	0.115	0.665
HDL-C (mmol/L)	1.16±0.24	1.17±0.28	1.18±0.29	0.253	0.381	0.918
LDL-C (mmol/L)	2.79±0.58	2.95±0.72	2.72±0.41	0.330	0.901	0.845
Cr (µmol/L)	56.74±11.20	57.58±15.46	56.44±9.75	0.232	0.203	0.270
UA (µmol/L)	321.83±8.56	312.00±116.01	305.11±80.03	0.375	0.547	0.123
ALT (U/L)	21.30±4.06	22.08±4.40	22.33±4.61	0.950	0.069	0.869
AST (U/L)	20.09±5.48	21.92±5.42	21.33±4.97	0.403	0.064	0.509
ALP (U/L)	75.17±23.54	72.83±27.30	77.22±22.93	0.825	0.634	0.236
r-GT (U/L)	31.74±15.72	31.00±18.99	30.33±16.29	1.00	0.662	0.478

Notes: Data presented as mean ± standard deviation or as a ratio.

^*P-value <0.05.

Abbreviations: FPG, fasting plasma glucose; FINS, fasting serum insulin; Cr, creatinine; UA, uric acid; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; r-GT, r-glutamyl transferase; HOMA-% B, homeostasis model assessment of steady-state beta cell function; HOMA-IR, homeostasis model assessment of insulin resistance; P1, P-values for changes in variables between baseline and follow-up at 12 weeks; P2, P-values for changes in variables between baseline and follow-up at 24 weeks; P3, P-values for changes in variables between follow-up at 12 weeks and 24 weeks; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides; TC, total cholesterol; HbA_1c, glycosylated hemoglobin.