Table 1.
| Nonclassical class I molecules | T cel subsets | ||||
|---|---|---|---|---|---|
| Mammals | Placental mammals | Human | CD1a | αβ T cells | |
| CD1b | γδ T cells | ||||
| CD1c | iNKT cells | ||||
| CD1d | Type II NKT cells | ||||
| CD1e | MAIT cells | ||||
| MR1 | |||||
| Mouse | αβ T cells | ||||
| CD1d | γδ T cells | ||||
| T22/T10 | iNKT cells | ||||
| MR1 | Type II NKT cells | ||||
| MAIT cells | |||||
| Dog | CD1a (x2) | ||||
| CD1b | αβ T cells | ||||
| CD1c | γδ T cells | ||||
| CD1d | iNKT cells(80) | ||||
| CD1e | |||||
| MR1 | |||||
| Rabbit | CD1a (x2) | αβ T cells | |||
| CD1b | γδ T cells | ||||
| CD1d | iNKT cells? | ||||
| CD1e | |||||
| Artiodactyls | Sheep |
CD1a(49) | αβ T cells | ||
| Cow | CD1b (x3)(49) | γδ T cells | |||
| CD1d(50) | MAIT cells(125) | ||||
| CD1e(49) | iNKT cells?(81) | ||||
| MR1(137) | |||||
| Horse | CD1a (x7)(48) | ||||
| CD1b(48) | αβ T cells | ||||
| CD1c(48) | γδ T cells | ||||
| CD1d (x2)(48) | iNKT cells(81) | ||||
| CD1e (x2)(48) | |||||
| MR1 | |||||
| Marsupials | Opossum | CD1 in some species(53) | αβ T cells | ||
| MR1(120) | γδ T cells | ||||
| MAIT cells(120) | |||||
| Monotremes | Platypus | ? | VHδ γδ T cells(164) | ||
| TCRμ T cells(172, 173) | |||||
| Birds | Chicken | chCD1-1, chCD1-2(45, 46) | αβ T cells | ||
| γδ T cells | |||||
| YF1*7.1(139) | VHδ γδ T cells(170) | ||||
| Reptiles | Squamata |
CD1(47) | αβ T cells only(141) |
||
| Testudines, Crocodylia | αβ and γδ T cells(141) | ||||
| Amphibians | Frog | αβ T cells | |||
| XNC(84) | γδ T cells | ||||
| VHδ γδ T cells(171) | |||||
| XNC10-invariantT(83) | |||||
| Cartilaginous fish | Shark | Hefr-19 (class Ib)(88) | αβ T cells | ||
| Gici-11 (predicted class Ib)(88) | γδ T cells | ||||
| Sqac-UAA*NC1(89) | IgM/W γδ T cells(147) | ||||
| NAR-TCR γδ T cells(175) | |||||