Table 3.
Multivariable Cox proportional hazards regression models based on 1, 3 and 5 years of follow-up along with time-dependent analysis
| Analysis/Yrs of FU included | Overall HR (95% CI) | Time-dependent HRs | p value for proportional hazards assumption | ||
|---|---|---|---|---|---|
| 1st | 2nd | 3rd | |||
| EUS vs. no EUS or CT-PET (1995–2008) | |||||
| 1 | 0.54 (0.46–0.62) | 0.39 | 0.65 | 0.68 | 0.0029 |
| 3 | 0.60 (0.53–0.67) | 0.45 | 0.73 | 0.72 | 0.0006 |
| 5 | 0.61 (0.54–0.68) | 0.46 | 0.78 | 0.69 | 0.0003 |
| EUS vs. no EUS or CT-PET (2002–2008) | |||||
| 1 | 0.49 (0.39–0.59) | 0.34 | 0.61 | 0.63 | 0.0199 |
| 3 | 0.57 (0.48–0.66) | 0.41 | 0.66 | 0.77 | 0.0025 |
| 5 | 0.59 (0.5–0.68) | 0.43 | 0.68 | 0.79 | 0.003 |
| CTPET vs. no EUS or CT-PET (2002–2008) | |||||
| 1 | 0.57 (0.51–0.64) | 0.36 | 0.84 | 0.82 | <.0001 |
| 3 | 0.66 (0.60–0.72) | 0.45 | 0.78 | 1.00 | <.0001 |
| 5 | 0.67 (0.61–0.73) | 0.46 | 0.79 | 1.02 | <.0001 |
| EUS+CTPET vs. no EUS or CT-PET (2002–2008) | |||||
| 1 | 0.49 (0.38–0.62) | 0.31 | 0.50 | 1.10 | 0.0002 |
| 3 | 0.58 (0.47–0.69) | 0.35 | 0.94 | 0.78 | <.0001 |
| 5 | 0.60 (0.49–0.71) | 0.37 | 0.95 | 0.78 | <.0001 |