Table 1. Patient Demographics and Disease Characteristics.
Patient | Age (years) | Sex | Disease Duration (years) | Baseline UCDAI Score | Baseline Calprotectin (μg/g) | Disease Extent | Extraintestinal Manifestations | Family Hx | Smoker | Prior Therapy | Ongoing Therapy |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 47 | F | 26 | 6 | 1161 | L-sided | iritis/uveitis | None | s/p 13 yrs | 5-ASA, Pred, herbal, VSL#3 | 5-ASA, Chinese herbs, curcumin |
2 | 25 | M | 6 | 9 | 692 | Pancolitis | pystomatitis vegetans | None | No | 5-ASA, AZA, infliximab | None |
3 | 61 | F | 40 | 8 | 366 | Pancolitis | none | Brother and son with UC | 1 cig/day | 5-ASA, Pred, herbal, VSL#3 | 5-ASA, boswellia |
5 | 29 | M | 7 | 6 | 280 | L-sided | none | Mom with UC | No | 5-ASA, VSL#3 | 5-ASA |
6 | 61 | F | 22 | 8 | 429 | L-sided | apthous stomatitis | Mom with UC | No | 5-ASA, AZA | None |
7 | 27 | F | 8 | 8 | 209 | L-sided | possible sacroiliitis | None | 1 cig/week | 5-ASA, Entocort, AZA | 5-ASA |
8 | 38 | F | 7 | 8 | ND | Pancolitis | none | None | No | 5-ASA, Pred, ABX, AZA, MTX, infliximab, adalimumab | None |
5-ASA = 5-aminosalicylic acid preparations, Pred = prednisone, AZA = azathioprine, ABX = antibiotics, MTX = methotrexate, UCDAI = ulcerative colitis disease activity index