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. Author manuscript; available in PMC: 2015 Aug 22.
Published in final edited form as: J Am Chem Soc. 2015 May 27;137(22):7011–7014. doi: 10.1021/jacs.5b02701

Figure 4.

Figure 4

Active site configuration in the ternary Dpo4 extension-step complex with primer dC opposite the MeFapy-dG, followed by dATP opposite template dT. (A) View into the DNA major groove, and (B) rotated by ∼90° around the horizontal axis and looking perpendicularly onto the nucleobase plane of the incoming dATP. Carbon atoms of the MeFapy-G:dC and dT:dATP pairs are colored in cyan and magenta, respectively