Table 3.

Generalised Estimating Equations parameter estimates for the effect of intervention on cortisol and amylase. The group by time interaction is verified for both biomarkers. There is difference in the linear effect of time between intervention and control for the amylase level (b = −72.166) and for the cortisol level (b = −0.071).

Parameter	B	SE	Wald chi-square	p value
Dependent variable: amylase level
(Intercept)	244.722	14.9182	269.101	<0.001
Intervention	42.749	23.6104	3.278	0.07
Time	37.367	3.3245	126.34	<0.001
Intervention ∗ time	−72.166	5.1623	195.428	<0.001
Dependent variable: cortisol level
(Intercept)	0.185	0.027	47.117	<0.001
Intervention	0.084	0.0358	5.467	0.019
Time	0.055	0.0094	34.167	<0.001
Intervention ∗ time	−0.071	0.0103	46.644	<0.001