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. Author manuscript; available in PMC: 2015 Aug 22.
Published in final edited form as: Nat Immunol. 2015 Apr 13;16(6):653–662. doi: 10.1038/ni.3148

Figure 3. TET1 is hypermethylated and transcriptionally down-regulated in B-NHL.

Figure 3

a) Methylation profiling by HELP-assay of the TET1 promoter in DLBCL and FL patients compared to normal naïve (NB) and centroblast (CB) B cells. b) mRNA expression analysis of TET1 in B-NHL patients. c) MassARRAY analysis of TET1 CpG methylation in 26 FL patients compared to normal Germinal Center B (GCB) cells and d) RNA-seq of TET1 and TET2 expression in the same 26 FL patients and normal GCB cells. Each circle indicates an individual patient in all panels; * P = <0.05, ** P = <0.005, *** P = <0.0005.

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