Fig. 1.

Sal-YB1 could suppress neuroblastoma growth in both nude and NOD-SCID mice. Tumor growth with/without Sal-YB1 treatment was assessed by a in vivo imaging system and b tumor size measurement. The tumors and kidneys were placed on a 30-mm-diameter dish. c Rate of ROI change was significantly different within either nude or NOD-SCID mice and also between these two groups (P < 0.05). d The post mortem tumor size increase rate post-YB1 treatment was reduced to 30 % in nude mice and 70 % in NOD-SCID mice when compared to control (P < 0.05). The error bars showed means ± SEM for four mice in each group. *P < 0.05 by an unpaired two-tailed t test