Fig. 2.

Sal-YB1 could induce cell death in neuroblastoma xenografts of both the nude and NOD-SCID mice. Tumors with YB1-treated and -untreated groups were evaluated by a flow cytometry (FCM), b hematoxylin and eosin (H&E), and c immunohistochemistry (IHC) staining, respectively. Salmonella could be detected within the tumor mass. Scale bar: 50 μm. d Bar diagrams of Annexin V/PI result with statistical analysis. The error bars showed means ± SEM for four mice in each group. *P < 0.05 and ^*** P < 0.001 by an unpaired two-tailed t test