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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Planta Med. 2015 Jul 1;81(0):1133–1140. doi: 10.1055/s-0035-1546118

Table 3.

Bioactivity evaluation of compounds isolated from B. cochinchinensis.a,b

Compound HT-29c NF-κB (p65)d P. falciparume
1 > 20 > 20 0.65 ± 0.06
2 13.2 > 20 1.28 ± 0.13
3 3.3 > 20 1.02 ± 0.09
4 > 20 > 20 0.26 ± 0.01
5 18.4 > 20 0.63 ± 0.02
6 > 20 > 20 > 10
7 1.9 > 20 2.07 ± 0.13
8 > 20 > 20 > 10
9 > 20 4.0 1.33 ± 0.37
Paclitaxelf 0.001 - -
Rocaglamideg - 0.08 -
Artemisininh - - 0.0007
a

No obvious growth inhibition of C. albicans cells were observed for the test compounds at a concentration of 40 mg/mL.

b

Results are expressed as ED50 or IC50 values (µM).

c

Compounds with ED50 values of > 20 µM in HT-29 cells are considered inactive.

d

Compounds with IC50 values of > 20 µM on an enzyme-based ELISA NF-κB (p65) assay are considered inactive.

e

Compounds with IC50 values of > 10 µM in P. falciparum assay are considered inactive.

f

Used as a positive control substance for the cytotoxicity assay.

g

Used as a positive control substance for the cytotoxicity assay.

h

Used as a positive control substance for the P. falciparum assay.