Table 2.
Yield of biopsies for detecting rejection stratified by era and biopsy type.
| Time | All patients | Early Era | Modern Era | |||
|---|---|---|---|---|---|---|
| Biopsies (N) | % with ACR (N) | Biopsies (N) | % with ACR (N) | Biopsies (N) | % with ACR (N) | |
| All Biopsies | ||||||
| 0–6 mo | 1615 | 8.8% (142) | 932 | 12.3% (115) | 683 | 4.0% (27) |
| 6–12 mo | 349 | 7.2% (25) | 255 | 9.4% (24) | 94 | 1.1% (1) |
| 12–36 mo | 633 | 7.0% (44) | 487 | 7.6% (37) | 146 | 4.8% (7) |
| Surveillance (Asymptomatic) Biopsies | ||||||
| 0–6 mo | 1416 | 7.3% (104) | 774 | 10.9% (84) | 642 | 3.1 % (20) |
| 6–12 mo | 293 | 5.8% (17) | 215 | 7.9% (17) | 78 | 0% (0) |
| 12–36 mo | 535 | 5.0% (27) | 407 | 6.1% (25) | 128 | 1.6 % (2) |
| Clinically Indicated (Symptomatic) Biopsies | ||||||
| 0–6 mo | 199 | 19.1% (38) | 158 | 19.6%(31) | 41 | 17.1% (7) |
| 6–12 mo | 56 | 14.3% (8) | 40 | 17.5% (7) | 16 | 6.3% (1) |
| 12–36 mo | 98 | 38.6% (17) | 80 | 15.0% (12) | 18 | 27.8% (5) |
ACR = acute cellular rejection; mo = month.