Table 2.
Effects of aging, hindlimb suspension and re-loading on body weight (BW), gastrocnemius muscle wet weight (MW) and gastrocnemius muscle weight to body weight ratio (MW/BW) in Fischer344×Brown Norway rats at 6 and 32 months of age.
Age
|
6-month
|
32-month
|
||||||
---|---|---|---|---|---|---|---|---|
Treatment | Control | HS | HS + 7-day | HS +14-day | Control | HS | HS + 7-day | HS +14-day |
BW (g) | 416 ± 10b | 325 ± 8a | 340 ± 10a | 355 ± 11a | 580 ± 19c | 463 ± 16b | 437 ± 6b | 450 ± 9b |
MW (g) | 2.16 ± 0.05e | 1.42 ± 0.03b | 1.57 ± 0.05c | 1.82 ± 0.06d | 1.58 ± 0.04bc | 1.04 ± 0.03a | 1.12 ± 0.03a | 1.18 ± 0.08a |
MW/BW (mg/g) | 5.11 ± 0.04e | 4.40 ± 0.05c | 4.67 ± 0.05d | 5.10 ± 0.03e | 2.75 ± 0.11b | 2.25 ± 0.06a | 2.65 ± 0.04b | 2.62 ± 0.18b |
Values are means±SEM (n=8).
a,b,c,d,eDifferent letters are significantly different from each other (p<0.05 by Tukey’s Multiple Comparison Test). The muscle weight is reported as the average weight of muscles from two legs. Control, non-suspended control; HS, 14 days of HS; HS+7, 14 days of HS followed by 7 days of ambulatory re-loading; HS+14, 14 days of HS followed by 14 days of ambulatory re-loading.