Table 1.
Recipient Characteristics at Transplant
| DDLT (n=464) | LDLT (n=963)* | p-value | |||||
|---|---|---|---|---|---|---|---|
| N | Mean (SD) or Frequency | Range or % | N | Mean (SD) or Frequency | Range or % | ||
| Age | 463 | 52.08 (10.49) | 18–74 | 963 | 51.37 (11.48) | 18–76 | 0.25 |
| Female | 464 | 182 | 39% | 963 | 408 | 42% | 0.26 |
| Hispanic | 463 | 87 | 19% | 963 | 126 | 13% | 0.005 |
| Race | 464 | 963 | <0.001 | ||||
| White | 390 | 84% | 877 | 91% | |||
| Black | 33 | 7% | 29 | 3% | |||
| Asian | 17 | 4% | 31 | 3% | |||
| Other Race | 24 | 5% | 26 | 3% | |||
| Body mass index | 412 | 26.78 (5.01) | 13–50 | 919 | 26.54 (5.26) | 15–55 | 0.42 |
| Diagnosis (multiple diagnoses possible) | 464 | 963 | |||||
| Acute liver failure | 19 | 4% | 24 | 2% | 0.10 | ||
| Alcohol-related cirrhosis | 86 | 19% | 155 | 16% | 0.25 | ||
| Autoimmune hepatitis | 20 | 4% | 63 | 7% | 0.09 | ||
| Cryptogenic cirrhosis | 53 | 11% | 80 | 8% | 0.06 | ||
| HBV | 12 | 3% | 28 | 3% | 0.73 | ||
| HCC | 98 | 21% | 154 | 16% | 0.02 | ||
| HCV | 210 | 45% | 339 | 35% | <0.001 | ||
| Hemochromatosis | 3 | 1% | 10 | 1% | 0.47 | ||
| Other metabolic liver disease | 16 | 3% | 21 | 2% | 0.16 | ||
| Malignancy other than HCC | 7 | 2% | 26 | 3% | 0.16 | ||
| PBC | 12 | 3% | 81 | 8% | <0.001 | ||
| PSC | 61 | 13% | 162 | 17% | 0.07 | ||
| Other diagnosis | 21 | 5% | 90 | 9% | 0.001 | ||
| MELD at evaluation | 452 | 16.77 (6.61) | 6–40 | 538 | 14.55 (6.00) | 6–40 | <0.001 |
| 6–10 | 67 | 15% | 130 | 24% | |||
| 11–10 | 267 | 59% | 348 | 65% | |||
| 21–30 | 97 | 21% | 44 | 8% | |||
| 31–40 | 21 | 5% | 16 | 3% | |||
| MELD at transplant | 440 | 20.42 (8.92) | 6–40 | 935 | 15.47 (5.90) | 6–40 | <0.001 |
| 6–10 | 52 | 12% | 169 | 18% | |||
| 11–10 | 201 | 46% | 614 | 66% | |||
| 21–30 | 118 | 27% | 132 | 14% | |||
| 31–40 | 69 | 16% | 20 | 2% | |||
| Medical condition at transplant | 462 | 567 | <0.001 | ||||
| Intensive care unit (ICU) | 51 | 11% | 9 | 2% | |||
| Hospitalized not in ICU | 70 | 15% | 35 | 6% | |||
| Not hospitalized | 341 | 74% | 523 | 92% | |||
| Comorbidities | |||||||
| Ventilator | 461 | 28 | 6% | 959 | 12 | 1% | <0.001 |
| Ascites | 455 | 284 | 62% | 567 | 260 | 46% | <0.001 |
| Dialysis | 457 | 25 | 5% | 957 | 7 | 1% | <0.001 |
|
| |||||||
| Perioperative Characteristics | N | Median | IQR | N | Median | IQR | p-value |
|
| |||||||
| Duration of recipient surgery (h) | 421 | 5.78 | 5–7 | 533 | 7.57 | 7–9 | <0.001 |
| Total ischemia time (min) | 442 | 486.50 | 364–600 | 847 | 98.00 | 71–140 | <0.001 |
| PRBCsδ | 439 | 6.00 | 3–11 | 557 | 4.00 | 2–8 | <0.001 |
| Recipient ICU LOS (days) | 370 | 2.00 | 1–5 | 915 | 2.00 | 1–3 | 0.05 |
| Recipient Total LOS (days) | 407 | 10.00 | 7–17 | 945 | 10.00 | 7–15 | 0.65 |
*
Excludes LDLT cases ≤ 20.
δ
Collected in A2ALL-1 only.
DDLT=deceased donor liver transplant; LDLT=living donor liver transplant; SD=standard deviation; HBV=hepatitis B virus; HCC=hepatocellular carcinoma; HCV=hepatitis C virus; PBC=primary biliary cirrhosis; PSC=primary sclerosing cholangitis; MELD=model for end-stage liver disease; IQR = interquartile range; PRBC = packed red blood cells; LOS = length of stay.