Table 3.
Frequency of WHO criteria in the different tumor subtypes
| Subgroups | All Patients | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| TPAs | APAs | PCAs | Total | ||||||
| N= | Mean | N= | Mean | N= | Mean | N= | Mean | ||
| Mitotic index (in 10 HPF) | 200 | 1 | 98 | 7 | 10 | 3 | 308 | 3 | |
| p53 pos. Nuclei (%) | 200 | 1 | 98 | 8 | 10 | 8 | 308 | 3 | |
| Ki-67 pos. Nuclei (%) | 200 | 1 | 98 | 9 | 10 | 7 | 308 | 4 | |
| Growth pattern | Non invasive | 77 | - | 8 | - | 0 | - | 85 | - |
| Invasive | 68 | - | 58 | - | 10 | - | 136 | - | |
Overview of metric and dichotomous parameters analyzed in the subgroups of pituitary tumors analyzed
N number, HPF High power field, TPA typical pituitary adenomas, APA atypical pituitary adenomas, PCA pituitary carcinomas