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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: J Thorac Oncol. 2015 Sep;10(9):1301–1310. doi: 10.1097/JTO.0000000000000617

Table 2.

Associations between peripheral blood cell count test or histologic inflammation scores and overall survival in the training cohort

Variables n % 5-year OS P * HR 95% CI
Complete blood count
White blood cell, No. 0.32
 Low (≤7) 125 39 62% ref.
 High (>7) 194 61 55% 1.17 (0.86 – 1.59)
Neutrophil, % 0.26
 Low (≤77) 264 83 60% ref.
 High (>77) 55 17 45% 1.24 (0.85 – 1.79)
Neutrophil, No. 0.92
 Low (≤4) 84 26 57% ref.
 High (>4) 235 74 58% 1.02 (0.72 – 1.43)
Lymphocyte, % 0.005
 Low (≤15) 71 22 38% ref.
 High (>15) 248 78 63% 0.62 (0.45 – 0.87)
Lymphocyte, No. 0.26
 Low (≤2) 257 81 55% ref.
 High (>2) 62 19 69% 0.80 (0.54 – 1.18)
Neutrophil/lymphocyte ratio 0.001
 Low (≤5.5) 266 83 62% ref.
 High (>5.5) 53 17 34% 1.82 (1.26 – 2.62)
Histologic inflammation scores
Acute inflammation, % 0.013
 Low (<5%) 212 64 60% ref.
 High (≥5%) 119 36 53% 1.46 (1.08 – 1.97)
Chronic inflammation, % 0.71
 Low (<10%) 196 59 59% ref.
 High (≥10%) 135 41 56% 1.06 (0.79 – 1.42)
Lymph follicles, No. 0.041
 Low (<5) 188 57 62% ref.
 High (≥5) 143 43 52% 1.35 (1.01 – 1.81)
*

P-values adjusting for pathologic stage. Significant P-values are shown in bold.

OS, overall survival; HR, hazard ratio; CI, confidence interval