Table 2. Protective immunity elicited by immunizing rTs-ES-1 in mice against challenge with 500 T. spiralis larvae.
Group | Mean adult worm burden ± SD (mouse#) | adult worm reduction | Mean muscle larvae per gram muscle ± SD (mouse#) | Muscle larvae burden reduction |
---|---|---|---|---|
PBS | 189 ± 19 (6) | 6532 ± 618 (6) | ||
ISA50V2+PBS | 197 ± 20 (6) | 6780 ± 938 (6) | ||
ISA50V2+ rTs-ES-1 | 138 ± 20 (6) | 27% * | 3782 ± 766 (6) | 42.1% * |
*p<0.01 compared with adjuvant control group.