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. Author manuscript; available in PMC: 2015 Aug 22.
Published in final edited form as: Biochim Biophys Acta. 2013 Feb 9;1830(6):3454–3457. doi: 10.1016/j.bbagen.2013.02.002

Fig. 3.

Fig. 3

Serum cytokine levels upon treatment with SC4, Zosyn and combination after P.a. bacteria challenge. SC4 (10 mg/kg) and Zosyn (400 mg/kg) were used in mouse bacteria model to assess cytokine serum levels of TNF-α (A), IL-1 (B) and IL-6 (C) after P.a. challenge. The compounds were administered by osmotic mini-pumps one day prior to i.p. injection of P.a. into C57/BL6 mice. Cytokines levels were assessed by ELISA (R&D systems, Minneapolis, MN). Data points shown are means of 2 independent experiments (n=2–4) ± SEM. *p < 0.03 (combination vs. control).