Skip to main content
. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2015 Feb 15;284(2):204–216. doi: 10.1016/j.taap.2015.02.008

Figure 1. Determination of the Median Lethal Dose (LD50) of soman for P21 male rats.

Figure 1

Fifty rats (10 rats per dose) were injected subcutaneously with soman at the following doses (μg/kg): 40, 55, 57.5, 62.5, and 70. Mortality rates were recorded at 24 hr following soman injection and used as the input data into the log-probit method of the IBM SPSS Statistics 20 package to determine the LD50. The plot shows the predicted mortality rates at different doses of soman at P21. The LD50 was 62.02 μg/kg (dashed line; p = 0.00414).