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. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2015 Feb 15;284(2):204–216. doi: 10.1016/j.taap.2015.02.008

Figure 4. Reduction of AChE activity in P21 rats after injection of 1.2 X LD50 soman.

Figure 4

Soman-exposed rats that did not develop SE were sacrificed 20 min after soman injection (No-SE group, n = 7). Rats that developed SE were sacrificed at the onset of SE (SE-onset group, n = 7). The soman-exposed rats of both groups had significantly lower AChE activity in all brain regions, compared to the control group (n = 5). AChE activity in the basolateral amygdala of the SE-onset group was significantly lower than that in the No-SE group. ***p < 0.001 compared to the control group, and *p < 0.05 between the no-SE and the SE-onset groups (One-way ANOVA with Tukey HSD post-hoc).