Table 3.

Genetic Origins of CGD

Subunit	Function	Gene	% of cases	Inheritance
NOX2	Catalytic	CYBB	65	X-linked
p22phox	Regulatory	CYBA	<5	Autosomal recessive
p47phox	Regulatory	NCF1	30	Autosomal recessive
p67phox	Regulatory	NCF2	<5	Autosomal recessive
p40phox	Regulatory	NCF4	Single case	Autosomal recessive