Table 2.
Nonspecific treatment effects on water deliveries, food, and water consumption in the home cage at baseline and after acute treatment (Mean ± SEM). An asterisk (*) represents a significant difference from vehicle (p<0.05).
| Operant Behavior | Home Cage Consumption | |||||||
|---|---|---|---|---|---|---|---|---|
| Water Deliveries | Food Consumption (g) | Water Consumption (g) | ||||||
| Treatment | Sex | n | Baseline | Acute | Baseline | Acute | Baseline | Acute |
| Vehicle | Males | 13 | 4.1 (1.0) | 3.7 (1.3) | 17.8 (0.4) | 18.4 (1.1) | 19.0 (0.6) | 19.2 (1.4) |
| Females | 15 | 6.4 (0.4) | 6.1 (1.5) | 14.4 (0.5) | 14.0 (0.6) | 21.7 (1.3) | 21.6 (1.6) | |
| 10-Top | Males | 13 | 4.4 (0.4) | 4.7 (0.4) | 18.6 (0.7) | 15.5 (1.4) | 20.1 (0.7) | 21.0 (1.2) |
| Females | 16 | 6.3 (0.4) | 5.9 (0.4) | 15.2 (0.5) | 13.3 (0.8) | 22.6 (1.6) | 21.8 (1.2) | |
| 20-Top | Males | 6 | 2.8 (0.5) | 2.2 (0.7)* | 16.4 (0.7) | 12.8 (1.0) | 19.7 (0.7) | 19.8 (1.2) |
| Females | 9 | 4.6 (0.4) | 6.0 (0.7)* | 15.8 (1.0) | 12.9 (1.3) | 27.0 (2.9) | 29.8(3.5) | |
| Nal | Males | 10 | 3.9 (0.5) | 2.3 0.6)* | 18.2 (0.7) | 15.5 (1.0) | 20.8 (0.8) | 17.6 (2.0) |
| Females | 9 | 6.1 (0.4) | 3.6 (0.4)* | 15.1 (0.8) | 13.9 (0.8) | 20.9 (1.5) | 23.3 (1.8) | |
| 10-Top +Nal | Males | 7 | 3.6 (0.5) | 3.0 (1.0) | 17.9 (0.9) | 14.1 (1.9) | 18.3 (0.4) | 19.3 (1.4) |
| Females | 9 | 5.8 (0.3) | 5.0 (0.5) | 15.4 (0.6) | 11.4 (1.2) | 22.0 (1.6) | 18.6 (1.7) | |